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A drug-food interaction occurs most commonly when the consumption of a specific food or beverage affects the activity of a drug or consumption of the drug affects the activity of the food or overall nutritional status.

When a food alters a drug’s activity or vice versa, the affected compound is changed in aspects of how quickly or how much of it gets absorbed into the body, how much of it distributes to it’s site of action, and how quickly it gets broken down or passed out from the body. Such drug-food interactions may result in the individual experiencing side effects, toxicity or not getting full benefit from the drug or food.

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Studies of drug interactions

contains a drug, the activity of another, in general, when both are administered simultaneously. These interactions in the decrease or increase in activity after one or two drugs. Although many forms of interactions are present, can be ordered in most interactions involving the travel of the drug, once (pharmacokinetics) or drug effect on the body (pharmacodynamics). that affect the travel of drugs in the body beyond those affecting the absorption into the bloodstream, its distribution in the body, divided into different products or even the body. can occur when drug particles have a large enough area to another drug because of particles to keep the two drugs can also bind to each other, or medication changes the acidity of stomach contents or the speed at which moves the contents of the stomach. These interactions can alter the ability of one or two drugs in the bloodstream. If one drug reduces the absorption of others, a patient is affected by regular use of these drugs in general. However, if a drug reduces the rate of absorption in another, the patient may be in the lower levels of the second drug most needed, and the second drug may be ineffective in the treatment will be suspended. when the drugs reach the blood and tissues. The competition between the two drugs can can bind to these same proteins in the blood or other drugs caused to move its relationship with tissue. It is more common in the second case, when replacing another medication to find tissue that displaced the drug in the blood leads to an increased risk of patients with toxicity accumulates. An example is when the heart medication Lanoxin ® and quinidine (digoxin) taken at the same time, may increase blood levels of digoxin and affect patients if not appropriately supervised. While the drugs can be located in different parts of the body which is broken site most often the liver. Here, an enzyme system are up-regulated or down regulated by a drug in the rapid deterioration or slower results of others. Examples of drugs that up-regulation of certain enzymes in the liver are among the most anti-epileptic Dilantin ® (phenytoin) and Tegretol ® (carbamazepine). The effect of the enzyme in place a regulation is usually done gradually, with maximum effects observed in 70-10 days after the start of the drug. It may also be equal to or greater than the time before normal after stopping the medication again. Examples of drugs that regulate certain enzymes in the liver are among the antibiotics erythromycin and ciprofloxacin. The beginning of the enzyme down-regulation is generally faster than upregulation. The majority of drugs down and all medicines out of the body by the loss of urine. When a drug affects the pH of urine, which may in the capacity of another drug in the urine, depending on how it received the form changes during the screening process in kidneys. Transporter molecules in the kidneys, the drug can help eliminate more or less available as a drug by the presence of another. Medications can also interact and exert a net effect of their direct actions on the body. Two drugs with similar effects, and if they can show synergy in action, while being administered in different sites or receptors in the body. One example is the fatigue that can occur when a tranquilizer such as Valium ® (diazepam) is also an antihistamine is like Polar Amine ® (dexchlorpheniramine hit). Conversely, if two drugs have opposite effects to be taken at the same time, the answer to one or both are reduced. An example of the opposing guard, and fatigue that can lead to the consumption of antimigraine preparation with caffeine and a sedative. Another set of measures related to drug interactions occur when the toxicity of using two drugs compared to the same organ or tissue in the body. Co-administration of both drugs can cause damage to the organ or tissue proper, despite the individual dose of each drug alone sufficient to cause toxic effects in a row under normal circumstances. The joint institutions that are most affected by this toxic drug interactions for the kidneys and liver. Note also that the drug may increase the toxic effect of the other body, although this is not a direct toxicity of the institution itself. Because many drugs available, and many others arrive constantly, drug interactions may be quite common. However, the negative effect of the consultation with an experienced drug are minimized. If such interactions are expected soon, the cons, the most appropriate measures are being prepared to receive the well-being maintained.

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